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Efficient and Fast Method for the Preparation of Diaryl Ketones at Room Temperature
Authors
Abdol Reza Hajipour, Raheleh Pourkaveh
Publication date
2014
Journal name
Synlett
Issue
EFirst
Publisher
© Georg Thieme Verlag
Description
Abstract Palladium-catalyzed cross-coupling reaction of arylboronic acids with acid
chlorides at room temperature under phosphine-free conditions affords the corresponding
aromatic ketones in excellent yields within short times. This synthetic method overcomes
common disadvantages of Friedel–Crafts acylation procedures and is compatible with both
electron-donating and electron-withdrawing substituents on the aryl ring of the acyl
chlorides.
chlorides at room temperature under phosphine-free conditions affords the corresponding
aromatic ketones in excellent yields within short times. This synthetic method overcomes
common disadvantages of Friedel–Crafts acylation procedures and is compatible with both
electron-donating and electron-withdrawing substituents on the aryl ring of the acyl
chlorides.
Publications
Month/Season:
Spring
Year:
2014