(BeDABCO) 2Pd2Cl6 as an efficient homogeneous catalyst for copper‐free Sonogashira cross‐coupling reaction

An efficient catalytic system using 1‐benzyl‐4‐aza‐1‐azoniabicyclo [2.2. 2] octane chloride 
and palladium chloride ((BeDABCO) 2Pd2Cl6) was developed for the Sonogashira reaction. 
In the presence of a catalytic amount of this efficient, stable homogeneous catalytic system 
that is non‐sensitive to air and moisture, various aryl halides were efficiently coupled with 
phenylacetylene in good yields in H2O at 50° C under copper‐free conditions. Benzyl dabco 
as an efficient ligand and also a quaternary ammonium salt had an efficient stabilizing ...