Dimeric ortho‐palladated homoveratrylamine as an efficient homogeneous catalyst for copper‐free Sonogashira cross‐coupling reaction

Abdol R Hajipour, Hannaneh Rahimi, Fatemeh Rafiee

2012/12/1

Applied Organometallic Chemistry

26

12

727

The catalytic activity of ortho-palladated [Pd {C6H2 (CH2CH2NH2)-(OMe) 2, 3, 4}(m-Br)] 2, a 
complex of homoveratrylamine in the copper-free Sonogashira coupling reaction has been 
investigated. This complex is a catalyst that is efficient, stable and non-sensitive to air and 
moisture in the Sonogashira reaction. In this homogeneous catalytic system, various aryl 
halides were efficiently coupled with phenylacetylene in mostly moderate to good yields in N-
methylpyrrolidone at 100 C under copperfree conditions. Copyright© 2012 John Wiley & ...